Dr. Paul Kent Langston PhD

Department of Immunology
Harvard Medical School
Boston, MA | USA

Dr. Kent Langston is a Postdoctoral Fellow in the laboratory of Drs. Diane Mathis and Christophe Benoist in the Department of Immunology at Harvard Medical School. Dr. Langston received his PhD from Harvard University for his work in Dr. Tiffany Horng’s laboratory on macrophage metabolism. His current work is centered on immunological regulation of the beneficial effects of exercise in youth and old age. In a recently published study, partly supported by an F32 award from the NIH/NIA, Dr. Langston showed that regulatory T cells (Tregs) are enriched in skeletal muscle following exercise and that such enrichment is necessary to control type I inflammation, in particular IFN-gamma, to permit the enhancements in muscle metabolism and function typical of long-term exercise training. The ultimate goal of Dr. Langston’s work is to unveil and translate basic mechanisms of exercise recognition and immunoregulation to expand the armamentarium of exercise-inspired therapies to combat inflammatory diseases and slow aging.